CMP 14, GGT, CRP,hs, ESR, Insulin, HgA1C, Homocysteine, Vitamin D 25 OH, Basic Lipid Panel
The Comprehensive Metabolic Panel (CMP14) is used in the evaluation of organ function and checks for conditions such as diabetes, liver disease, and kidney disease. The CMP may also be ordered to monitor conditions, such as hypertension, and to monitor patients taking medications for any kidney- or liver-related side effects. If a doctor is interested in following two or more individual CMP components, they may order the entire CMP because it offers more information and can give a more thorough assessment.
GGT is used to determine why a patient would have elevated levels of alkaline phosphatase or also known as ALP. This test would be recommended for any patients with disease associated with the bile duct, and also for patients who have liver or bone disease.
C-Reactive Protein, hs: Increases when there’s inflammation in your body. This test can also be used to evaluate your risk of developing coronary artery disease.
Sedimentation Rate, Westergren (ESR): The Sedimentation Rate test is used to evaluate the nonspecific activity of infections, inflammatory states, autoimmune disorders, and plasma cell dyscrasias.
Insulin: This test is used to diagnose an insulin-producing tumor and verify that the removal of the tumor has been successful. It can also be used to diagnose hypoglycemia, insulin resistance, and can be paired with a C-peptides test to determine levels of insulin being produced in the body, and levels of insulin coming from an outside source such as insulin injections.
Hemoglobin A1c: Diabetes and prediabetes in adults can be diagnosed and screened for using this test. When glucose attaches to hemoglobin, hemoglobin A1c is then created. When glucose levels are elevated, more glycated hemoglobin is created.
Homocysteine: This test is ordered for a variety of clinical purposes including heart conditions, and vitamin b12 or folate deficiency. Testing homocysteine can be effective in identifying abnormal levels of B12 and folate before symptoms are present.
Vitamin D-25 Hydroxy: Vitamin D-25 Hydroxy is ordered when an individual has low calcium and/or symptoms of vitamin D deficiency. This can appear as bone weakness/softness, or fractures in adults, or as rickets (bone malformation) in children.
The vitamin D test is for individuals at high risk of deficiency. It is used to monitor diseases that interfere with fat absorption. These diseases include cystic fibrosis or Crohn disease. This test also monitors the effectiveness of Vitamin D-25 Hydroxy, calcium, magnesium or phosphorus supplementation.
Individuals at risk of vitamin D deficiency include: older adults, individuals who have limited exposure to sunlight, individuals who are obese, or who have fat malabsorption.
Low levels of D-25 hydroxy are one of the earliest changes that show in individuals with early kidney failure. People with kidney disease also show low levels.
High levels of D-25 hydroxy show due to diseases that can make Vitamin D-25 Hydroxy outside of the kidneys. The two primary diseases related to this are sarcoidosis or certain lymphomas.
Long term high levels of vitamin D can eventually lead to the damage of certain organs such as the kidneys and blood vessels via calcification. If magnesium levels are low, a physician may supplement both magnesium and calcium in order to eliminate a low calcium level that is resistant to Vitamin D-25 Hydroxy.
Basic Lipid Panel: This test measures Cholesterol, total; high-density lipoprotein (HDL) cholesterol; low-density lipoprotein (LDL) cholesterol (calculation); triglycerides; very low-density lipoprotein (VLDL) cholesterol (calculation).