Metabolic Panel Plus

METABOLIC PANEL PLUS: Includes Kryptopyrrole Urinary Quantitative, Copper Serum, Zinc Plasma, Whole Blood Histamine and Ceruloplasmin. The Metabolic Panel Plus aids the practitioner in assessing levels of nutrients that are critical to brain health and in calculating free copper/oxidative stress. The Metabolic Panel Plus identifies imbalances that have been associated with Autism, Asperger syndrome, ADD/HD, anxiety, Bipolar disorder, assaultive/aggressive/violent behavior, other mental and emotional conditions and schizophrenia. The Kryptopyrrole Urinary Quantitative is an at-home collection kit. The at-home Kryptopyrrole collection kit includes all collection materials shipped to you, overnight return shipping back to our laboratory, running the test, reporting the results, and a receipt for services rendered that you can submit for insurance reimbursement.

The Whole Blood Histamine, Copper Serum, Zinc Plasma, and Ceruloplasmin will require a blood draw. We will provide the patient with several patient service centers centrally located around the shipping address, instructions, and a laboratory requisition. The patient service center will handle the specimen collection to the requirements of our laboratory. These specimen collection requirements and methodologies are unique. They were modeled by the Original Pfeiffer Treatment Center, Founded by Dr. William J. Walsh. Performing specimen collections to these specifications will allow doctors and patients to have more accurate results that can be placed into personalized optimal functional ranges. We demand only the best specimen collection and transportation available. All of our orders include extensive and award winning customer service.

Pyrroles, Copper, Zinc, & Histamine -THE REPEAT OFFENDERS: “For several years I was perplexed by the repeated presence of certain biochemical imbalances in completely different mental disorders. For example, copper overload is present in most cases of hyperactivity, learning disability, post-partum depression, autism, and paranoid schizophrenia. In another example, undermethylation is often present in antisocial personality disorder, clinical depression, anorexia, obsessive-compulsive disorder, and schizoaffective disorder. The primary repeat offenders are copper overload, B-6 deficiency, zinc deficiency, methyl/folate Imbalances, pyrrole disorder, and amino acid imbalances. Eventually I realized these factors had something in common and a direct role in the synthesis or functioning of a major neurotransmitter.” – Dr. William J. Walsh

Ceruloplasmin is used in the evaluation of oxidative stress. When paired with copper, it is used to calculate free copper. When paired with other blood or urine copper tests, ceruloplasmin is used to help diagnose Wilson’s disease. This is due to a decreased ability to incorporate copper into apoceruloplasmin. In turn, free copper levels in plasma and tissue are greatly increased, especially in the liver and brain.

An estimated 95% of copper in the blood is bound to ceruloplasmin.  As a result, only a very small amount of copper is found in the blood in an unbound or free state.

If you do not have a practitioner that will order this testing for you, you can order this test directly. Ordering direct does not include medical management regarding the test results.

Requires a urine specimen and blood draw.

Patient Preparation
Kryptopyrrole Quantitative Urine: Do not collect the first morning urine specimen. A second morning urine collection is preferred, but not required. Supplements containing vitamins or minerals should be stopped 12-24 hours prior to your urine collection. Antibiotics may cause an interfering substance and create a result that cannot be reported. However, do not go off any prescription medications unless advised by your ordering physician.

Bloodwork: A fasting specimen is preferred, but not required. Patients can fast for 12 hours prior to specimen collection. Supplements containing vitamins or minerals should be stopped 12-24 hours prior to your blood draw. Do not avoid supplements for longer than 24 hours. Sports drinks and energy drinks such as Redbull or Vitamin Water are known to contain levels of vitamins and minerals that would classify them as supplements. Please look at the vitamin and mineral information on your products. If they are considered a supplement, like Ensure, please discontinue them 12 hours prior to specimen collection. Anti-histamines, if approved by your practitioner, should be stopped 21 days prior to your blood draw.